Medical Articles
Julian B. Wilson1, Thanh D. Hoang2, Martin L. Lee1,3, Ma’ayan Epstein 1,3 Theodore C. Friedman 1,4* 1 Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California, United States of America, 2 Endocrinology Division, Walter Reed National Military Medical Center, Bethesda, Maryland, United […]
A 24-hour urine collection (also known as a urinary free cortisol test or UFC) is an essential diagnostic tool used to measure
Night-time salivary cortisol testing is an essential, non-invasive tool that helps detect abnormalities in cortisol levels—particularly
Dr. Friedman's main approach to weight loss is to rule out any endocrine problems, such as hypothyroidism, Cushing syndrome, or growth hormone deficiency, that may lead to weight gain.
Understanding Thyroid Hormones: T4 and T3 The thyroid makes two hormones, T4 which has a long half-life meaning it can be given once a day. T4 gets converted to T3 which is the active form of the hormone and has a short-half life, meaning it has to be given frequently. Most patients with hypothyroidism are […]
There are some supplements that can be used to lower the TPO antibody. Selenium at 200 mcg a day (can be purchased at Trader Joes or online) can lower the TPO antibody as can Myo-Inositol plus from Omnibiotics, 2000 mg/50 mg once a day that can be purchased on Amazon. These supplements are helpful in […]
Dr. Friedman, when he was a fellow at the NIH in the 1990s, published a paper in the Journal of Clinical Endocrinology and Metabolism on the timing of giving glucocorticoids to patients with Addison disease. This paper involved sleep studies, and Dr. Friedman and colleagues found that a small dose of hydrocortisone given at bedtime […]
There is some confusion about the role of anti-thyroglobulin antibodies in diagnosing Hashimoto’s. A large study using a national database called the NHANES database showed that only the TPO antibodies correlated with hypothyroidism and not anti-thyroglobulin antibodies. The confusion seems to come that before the TPO antibody was identified, doctors used a test called an […]
Dr. Friedman’s patient Dr. Madonna Ramp tragically passed away on November 12, 2024. She had adrenal insufficiency and was hospitalized for the last 5 months of her life.Madonna is the fourth patient of Dr. Friedman who tragically passed away who had adrenal insufficiency. Dr. Friedman was interviewed by Yahoo about the passing of TikTok star Taylor Rousseau Grigg who […]
Understanding Adrenal Hormones The adrenals make 2 important hormones, cortisol (a glucocorticoid) and aldosterone (a mineralocorticoid). Patients with adrenal insufficiency from an adrenal cause such as an adrenalectomy or Addison’s disease require replacement of both hormones, Although the natural mineralocorticoid is aldosterone, we give fludrocortisone or Florinef as a replacement. Florinef is the brand name […]
